CA15-3 ELISA Kit (Human) : 96 Wells (OKCA00009) | Aviva Systems Biology OKCA00009 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

CA15-3 ELISA Kit (Human) : 96 Wells (OKCA00009)

catalog :

OKCA00009

quantity :

96 Wells

product information

sku :

OKCA00009

product type :

Application Kit

category :

ELISA Kits

name :

CA15-3 ELISA Kit (Human) : 96 Wells (OKCA00009)

size :

96 Wells

gene symbol :

CA15-3

alias symbols :

Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, EMA, Episialin, H23AG, KL-6, MAM6, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, Mucin-1, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor-associated epith

nucleotide accession num :

NM_001018016

protein accession num :

NP_001018016

swissprot id :

P15941

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 211]

assay info :

Assay Methodology: Quantitative Sandwich Immunoassay

sensitivity :

< 2.5 U/ml

specificity :

This assay has high sensitivity and excellent specificity for detection of human CA15-3. No significant cross-reactivity or interference between human CA15-3 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between human CA15-3 and all the analogues, therefore, cross reaction may still exist.

drywet surcharge :

Wet Ice

storage temperature :