Kininogen-1/KNG1 ELISA Kit (Human) (OKBB00653) | Aviva Systems Biology OKBB00653 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

Kininogen-1/KNG1 ELISA Kit (Human) (OKBB00653)

catalog :

OKBB00653

quantity :

96 Wells

product information

sku :

OKBB00653

product type :

Application Kit

category :

ELISA Kits

name :

Kininogen-1/KNG1 ELISA Kit (Human) (OKBB00653)

size :

96 Wells

gene symbol :

KNG1

alias symbols :

Alpha-2-thiol proteinase inhibitor, BDK, Fitzgerald factor, High molecular weight kininogen, HMWK, Kininogen-1, KNG, Williams-Fitzgerald-Flaujeac factor

nucleotide accession num :

NM_000893.3

protein accession num :

NP_000884.1

swissprot id :

P01042

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

Kininogen-1 (KNG1), also known as alpha-2-thiol proteinase inhibitor, Williams-Fitzgerald-Flaujeac factor or the HMWK-kallikrein factor, is a protein that in humans is encoded by the KNG1 gene. It is mapped to 3q27.3. The KNG1 gene uses alternative splicing to generate two different proteins â€“ high â€“ molecular - weight kininogen (HMWK) and low - molecular- weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. In addition to that, KNG1 is a constituent of the blood coagulation system as well as the kinin-kallikrein system.

application :

ELISA

assay info :

Assay Methodology: Quantitative Sandwich Immunoassay

sensitivity :

<= 20 pg/mL

drywet surcharge :

Wet Ice

storage temperature :