Cystatin B ELISA Kit (Human) (OKBB00539) | Aviva Systems Biology OKBB00539 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

Cystatin B ELISA Kit (Human) (OKBB00539)

catalog :

OKBB00539

quantity :

96 Wells

product information

sku :

OKBB00539

product type :

Application Kit

category :

ELISA Kits

name :

Cystatin B ELISA Kit (Human) (OKBB00539)

size :

96 Wells

gene symbol :

CSTB

alias symbols :

CPI-B, CST6, Cystatin-B, EPM1, Liver thiol proteinase inhibitor, PME, Stefin-B, STFB

nucleotide accession num :

NM_000100.3

protein accession num :

NP_000091.1

swissprot id :

P04080

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

Cystatin B (CSTB), also called STFB, is a small protein that is a member of the superfamily of cysteine protease inhibitors. It has been isolated from human spleen and liver and its amino acid sequence has been fully determined. The cystatin B gene is located on 21q22.3. It is widely distributed and is localized mostly intracellularly, but has been found extracellularly. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Its role is thought to be as a protector against the proteinases leaking from lysosomes. A cystatin B multiprotein complex might have a specific cerebellar function, and that the loss of this function might contribute to the etiopathogenesis of EPM1. Upon differentiation to myotubes, CSTB becomes excluded from the nucleus and lysosomes, suggesting that the subcellular distribution of CSTB is dependent on the differentiation status of the cell.

application :

ELISA

assay info :

Assay Methodology: Quantitative Sandwich Immunoassay

sensitivity :

<= 10 pg/mL

drywet surcharge :

Wet Ice

storage temperature :