Elafin/PI3 ELISA Kit (Human) (OKBB00497) | Aviva Systems Biology OKBB00497 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

Elafin/PI3 ELISA Kit (Human) (OKBB00497)

catalog :

OKBB00497

quantity :

96 Wells

product information

sku :

OKBB00497

product type :

Application Kit

category :

ELISA Kits

name :

Elafin/PI3 ELISA Kit (Human) (OKBB00497)

size :

96 Wells

gene symbol :

PI3

alias symbols :

cementoin, Elafin, ELAFIN, Elastase-specific inhibitor, ESI, MGC13613, Peptidase inhibitor 3, PI-3, Protease inhibitor WAP3, SKALP, Skin-derived antileukoproteinase, WAP3, WAP four-disulfide core domain protein 14, WFDC14

nucleotide accession num :

NM_002638.3

protein accession num :

NP_002629.1

swissprot id :

P19957

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

Elafin, also known as peptidase inhibitor 3 or skin-derived antileukoproteinase (SKALP) is a protein that in humans is encoded by the PI3 gene. It is mapped to 2q13.12. This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 2q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. This gene is the neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis.

application :

ELISA

assay info :

Assay Methodology: Quantitative Sandwich Immunoassay

sensitivity :

<= 10 pg/mL

drywet surcharge :

Wet Ice

storage temperature :