Syndecan-4/SDC4 ELISA Kit (Human) (OKBB00392) | Aviva Systems Biology OKBB00392 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

Syndecan-4/SDC4 ELISA Kit (Human) (OKBB00392)

catalog :

OKBB00392

quantity :

96 Wells

product information

sku :

OKBB00392

product type :

Application Kit

category :

ELISA Kits

name :

Syndecan-4/SDC4 ELISA Kit (Human) (OKBB00392)

size :

96 Wells

gene symbol :

SDC4

alias symbols :

amphiglycan, Amphiglycan, MGC22217, ryudocan, Ryudocan core protein, SYND4, Syndecan-4

nucleotide accession num :

NM_002999.3

protein accession num :

NP_002990.2

swissprot id :

P31431

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

Syndecan-4 (SDC4) is a protein that in humans is encoded by the SDC4 gene. The protein is found as a homodimer and is a member of the syndecan proteoglycan family. It is mapped to 2q13.12. Syndecan-4 is one of the four vertebrate syndecans and has a molecular weight of ~2 kDa. It is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. Syndecan-4 also regulates the actin cytoskeleton, cell adhesion, and cell migration. In addition, Syndecan-4 can activate protein kinase C (PKC). The variable domain of syndecan-4 could be a site of self-association. Whatâ€™s more, Syndecan-4 also binds to phosphatidylinositol (4,5)-bisphosphate (PIP2) through the variable domain and increases PKC activity ten-fold.

application :

ELISA

assay info :

Assay Methodology: Quantitative Sandwich Immunoassay

sensitivity :

<= 10 pg/mL

drywet surcharge :

Wet Ice

storage temperature :