MIF ELISA Kit (Human) (OKBB00331) | Aviva Systems Biology OKBB00331 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

MIF ELISA Kit (Human) (OKBB00331)

catalog :

OKBB00331

quantity :

96 Tests

product information

sku :

OKBB00331

product type :

Application Kit

category :

ELISA Kits

name :

MIF ELISA Kit (Human) (OKBB00331)

size :

96 Tests

gene symbol :

MIF

alias symbols :

Macrophage migration inhibitory factor, Glycosylation-inhibiting factor, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase

nucleotide accession num :

NM_002415.1

protein accession num :

NP_002406.1

swissprot id :

P14174

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

Macrophage migration inhibitory factor (MIF) is a protein which in humans is encoded by the MIF gene. This gene is located to human chromosome 22q11.2. It is remarkably small; it has 3 exons separated by introns of only 189 and 95 bp, and covers less than 1 kb. This gene encodes a lymphokine that may be involved in cell-mediated immunity, immunoregulation, and inflammation. MIF plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein might form a complex in the cytosol near the peripheral plasma membrane, which may possibly indicate a role in integrin signaling pathways. MIF also plays a central role in the toxic response to endotoxemia and possibly septic shock.Macrophage migration inhibitory factor has been reported to interact with COP9 constitutive photomorphogenic homolog subunit 5, CD74, BNIPL, and CXCR4. The standard product used in this kit is recombinant human MIF, consisting of 115 amino acids with the molecular mass of 12.5kDa.

application :

ELISA

homology :

No detectable cross-reactivity with any other cytokine.

sensitivity :

< 20 pg/ml

specificity :

There is no detectable cross-reactivity with other relevant proteins.

drywet surcharge :

Wet Ice

storage temperature :