VCAM-1 ELISA Kit (Human) (OKBB00269) | Aviva Systems Biology OKBB00269 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

VCAM-1 ELISA Kit (Human) (OKBB00269)

catalog :

OKBB00269

quantity :

96 Tests

product information

sku :

OKBB00269

product type :

Application Kit

category :

ELISA Kits

name :

VCAM-1 ELISA Kit (Human) (OKBB00269)

size :

96 Tests

gene symbol :

VCAM1

alias symbols :

VCAm1, L1CAM, Vascular cell adhesion protein 1, CD106

nucleotide accession num :

NM_001078.3

protein accession num :

NP_001069.1

swissprot id :

P19320

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface glycoprotein adhesive for certain blood leukocytes and tumor cells, which is expressed by activated endothelium in a variety of pathologic conditions including atherosclerosis.1 Increased expression of VCAM1 is associated with a variety of chronic inflammatory conditions, making its expression and function a target for therapeutic intervention.2 Integrin alpha4beta1 (VLA-4) and VCAM-1 facilitate a critical cell-cell adhesion event required for survival of endothelial and mural cells during vascularization.3 The VCAM1 gene is assigned to the 1p31-32 region of chromosome 1 based on the analysis of human-mouse hybrid cell lines and in situ hybridization.1 The standard product used in this kit is recombinant human VCAM-1, consisting of Phe25-Glu698 amino acid sequence of a single chain with the molecular mass of 74KDa. As a result of glycosylation, the molecular mass of 9-95KDa is revealed by SDS-PAGE.

application :

ELISA

sensitivity :

< 10 pg/mL

specificity :

Natural and recombinant human VCAM-1. No detectable cross-reactivity with other relevant proteins

drywet surcharge :

Wet Ice

storage temperature :