TRAIL ELISA Kit (Human) (OKBB00266) | Aviva Systems Biology OKBB00266 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

TRAIL ELISA Kit (Human) (OKBB00266)

catalog :

OKBB00266

quantity :

96 Tests

product information

sku :

OKBB00266

product type :

Application Kit

category :

ELISA Kits

name :

TRAIL ELISA Kit (Human) (OKBB00266)

size :

96 Tests

gene symbol :

TNFSF10

alias symbols :

TNFSF10, APO2L, TRAIL, Tumor necrosis factor ligand superfamily member 10, Apo-2 ligand, TNF-related apoptosis-inducing ligand

nucleotide accession num :

NM_001190942.1

protein accession num :

NP_001177871.1

swissprot id :

P50591

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

In the field of cell biology, TNF-related apoptosis-inducing ligand (TRAIL), is a protein which functions as a ligand which induces the process of cell death called apoptosis. TRAIL has also been designated CD253 (cluster of differentiation 253).Tumor necrosis factor (TNF) family cytokines function as prominent mediators of immune regulation and the inflammatory response. Most TNF family cytokines are expressed as type II transmembrane proteins, with homology confined to approximately 15 C-terminal residues. The TNF ligands interact with a parallel family of receptors. TRAIL binds to the death receptors DR4 (TRAIL-RI) and DR5 (TRAIL-RII). The process of apoptosis is caspase-8-dependent. Caspase-8 activates downstream effector caspases including procaspase-3, -6, and -7, leading to activation of specific kinases. TRAIL also binds the receptors DcR1 and DcR2, which do not contain a cytoplasmic domain (DcR1) or contain a truncated death domain (DcR2). The standard product used in this kit is recombinant human TRAIL with the molecular mass of 21KDa. It is expressed from the amino acids ectoderm T95--G281.

application :

ELISA

homology :

No detectable cross-reactivity with any other cytokine.

sensitivity :

< 1 pg/mL

specificity :

There is no detectable cross-reactivity with other relevant proteins.

drywet surcharge :

Wet Ice

storage temperature :