PDGF-AB ELISA Kit (Human) (OKBB00239) | Aviva Systems Biology OKBB00239 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

PDGF-AB ELISA Kit (Human) (OKBB00239)

catalog :

OKBB00239

quantity :

96 Tests

product information

sku :

OKBB00239

product type :

Application Kit

category :

ELISA Kits

name :

PDGF-AB ELISA Kit (Human) (OKBB00239)

size :

96 Tests

gene symbol :

PDGFA

alias symbols :

PDGF1, PDGF-A

nucleotide accession num :

NM_002607.5

protein accession num :

NP_002598.4

swissprot id :

P04085

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

The platelet-derived growth factor (PDGF) is a mitogen derived from human platelets consisting of two related polypeptides termed A and B chains.1 The genes for PDGF A chain, B chain/c-sis, and the PDGF receptor are expressed in human malignant glioma cell lines.2 Normal human endothelial cells in culture express the B chain of PDGF, and that endothelial-derived PDGF B chain is synthesized as a predicted precursor polypeptide of Mr 27,281.3 The entire B chain of PDGF is highly (96%) homologous to a portion of p28sis, the transforming protein of simian sarcoma virus (SSV). It has been suggested that p28sis exerts its transforming potential by mimicking the growth promoting activity of PDGF and stimulating the cell in an autocrine manner.1 PDGF A-chain precursor polypeptide is assigned to the proximal long arm of chromosome 7, band q11.23.4 The human homolog (PDGF B-chain/c-sis) of the transforming gene of simian sarcoma virus is assigned to chromosome 22.5 The standard product used in this kit is recombinant human PDGF-AB with the molecular mass of 27KDa.

application :

ELISA

homology :

No detectable cross-reactivity with any other cytokine.

sensitivity :

< 2 pg/mL

specificity :

There is no detectable cross-reactivity with other relevant proteins.

drywet surcharge :

Wet Ice

storage temperature :