Leptin ELISA Kit (Human) (OKBB00206) | Aviva Systems Biology OKBB00206 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

Leptin ELISA Kit (Human) (OKBB00206)

catalog :

OKBB00206

quantity :

96 Tests

product information

sku :

OKBB00206

product type :

Application Kit

category :

ELISA Kits

name :

Leptin ELISA Kit (Human) (OKBB00206)

size :

96 Tests

gene symbol :

LEP

alias symbols :

Obese protein, Obesity factor, OB, OBS, LEP

nucleotide accession num :

NM_000230.2

protein accession num :

NP_000221.1

swissprot id :

P41159

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

Leptin (or obese, OB) is a circulating hormone that is expressed abundantly and specifically in the adipose tissue.1 Human ob protein is a 166-amino acid polypeptide with a putative signal sequence and is 84 and 83% homologous to the mouse and rat ob proteins, respectively.2 Northern blot analysis reveals that OB RNA is present at a high level in adipose tissue but at much lower levels in placenta and heart.3 Indeed, Leptin is first described as an adipocyte-derived signalling factor, which, after interaction with its receptors, induces a complex response including control of bodyweight and energy expenditure. Leptin seems in addition to its role in metabolic control to have important roles in reproduction and neuroendocrine signalling.4 Leptin is a powerful inhibitor of bone formation in vivo.5 Comparative mapping of mouse and human DNA indicates that the ob gene is located within a region of mouse chromosome 6 that is homologous to a portion of human chromosome 7q.3 The standard product used in this kit is recombinant human Leptin.

application :

ELISA

homology :

No detectable cross-reactivity with any other cytokine

sensitivity :

< 10 pg/mL

specificity :

There is no detectable cross-reactivity with other relevant proteins.

drywet surcharge :

Wet Ice

storage temperature :