ELISA/assay

IL10 ELISA Kit (Human) (OKBB00193)

OKBB00193

96 Tests

Application Kit

ELISA Kits

IL10 ELISA Kit (Human) (OKBB00193)

96 Tests

IL10

Interleukin-10, Interleukin 10, IL10, IL-10

NM_000572.2

NP_000563.1

P22301

Human

Store as indicated in product manual.

Interleukin-1, also called cytokine synthesis inhibitory factor, is implicated in tumorigenesis, and it has been shown that polymorphisms in its gene promoter correlate with differential amounts of production.1 IL-1 is an important cytokine with anti-inflammatory, anti-immune, and antifibrotic functions.2 It is also an important regulatory cytokine whose involvement extends into diverse areas of the human immune system.3 IL-1 is a recently described natural endogenous immunosuppressive cytokine that has been identified in human, murine, and other organisms. IL-1 significantly affects chemokine biology, because human IL-1 inhibits chemokine production and is a specific chemotactic factor for CD8+ T cells. It suppresses the ability of CD4+ T cells, but not CD8+ T cells, to migrate in response to IL-8.4 Interleukin-1 gene polymorphisms and interleukin-1 production capability may contribute to the development of skin squamous cell carcinomas after renal transplantation.1 The interleukin-1 locus contributes to the heritability of psoriasis susceptibility.5 With regard to sudden infant death, IL-1 is of special interest. This is an immunoregulatory cytokine that plays an important role in the development of infectious disease.6 The mIL-1 gene is mapped to mouse chromosome 1 and the hIL-1 gene is also mapped to human chromosome 1.7 The standard product used in this kit is recombinant human IL-1, consisting of 16 amino acids with the molecular mass of 18.6KDa.

ELISA

No detectable cross-reactivity with any other cytokine.

< 0.5 pg/ml

There is no detectable cross-reactivity with other relevant proteins.

Wet Ice

4C