IL-6 ELISA Kit (Human) (OKBB00189) | Aviva Systems Biology OKBB00189 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

IL-6 ELISA Kit (Human) (OKBB00189)

catalog :

OKBB00189

quantity :

96 Tests

citations: 1

Reference
Zhu K, Lv Z, Xiong J, Zheng H, Zhang S, Jin H, et al. MET inhibitor, capmatinib overcomes osimertinib resistance via suppression of MET/Akt/snail signaling in non-small cell lung cancer and decreased generation of cancer-associated fibroblasts. Aging (Albany NY). 2021;13:6890-6903 pubmed publisher

product information

sku :

OKBB00189

product type :

Application Kit

category :

ELISA Kits

name :

IL-6 ELISA Kit (Human) (OKBB00189)

size :

96 Tests

gene symbol :

IL-6

alias symbols :

Interleukin-6, Interleukin 6, IL 6, IFNB2

nucleotide accession num :

NM_000600.4

protein accession num :

NP_000591.1

swissprot id :

P05231

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

The human interferon-beta 2 gene (IFNB2) product is identical to that for the B-cell stimulation factor-2 (BSF-2), the hybridoma growth factor (HGF) ("interleukin-6"), and the hepatocyte stimulating factor (HSF). Proteins derived from this gene mediate the plasma protein response to tissue injury (acute-phase response) and regulate the growth and differentiation of both B and T cells.1 Interleukin-6 (IL6) has come to be regarded as a potential osteoporotic factor because it has stimulatory effects on cells of the osteoclast lineage, and, thus, may play a role in the pathogenesis of bone loss associated with estrogen deficiency.2 IL-6 has many roles essential to the regulation of the immune response, hematopoiesis, and bone resorption.3 It is involved not only in the hepatic acute phase response but also in adipose tissue metabolism, lipoprotein lipase activity, and hepatic triglyceride secretion.4 Overproduction of IL-6, a proinflammatory cytokine, is associated with a spectrum of age-related conditions including cardiovascular disease, osteoporosis, arthritis, type 2 diabetes, certain cancers, periodontal disease, frailty, and functional decline.5 BSF-2 is a novel interleukin consisting of 184 amino acids.6 The standard product used in this kit is recombinant human IL-6, consisting of 184 amino acids with the molecular mass of 2.3kDa.

application :

ELISA

homology :

No detectable cross-reactivity with any other cytokine.

sensitivity :

< 0.3 pg/ml

specificity :

There is no detectable cross-reactivity with other relevant proteins.

drywet surcharge :

Wet Ice

storage temperature :