FASL ELISA Kit (Human) (OKBB00143) | Aviva Systems Biology OKBB00143 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

FASL ELISA Kit (Human) (OKBB00143)

catalog :

OKBB00143

quantity :

96 Tests

product information

sku :

OKBB00143

product type :

Application Kit

category :

ELISA Kits

name :

FASL ELISA Kit (Human) (OKBB00143)

size :

96 Tests

gene symbol :

FASLG

alias symbols :

FASL, APTL, Apoptosis (APO 1) antigen ligand 1, Apoptosis antigen ligand, Tumor necrosis factor ligand superfamily member 6

nucleotide accession num :

NM_000639.2

protein accession num :

NP_000630.1

swissprot id :

P48023

species reactivity :

Human

reconstitution and storage :

Store as indicated in product manual.

description of target :

Fas ligand (FasL or CD95L) is a type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Its binding with its receptor induces apoptosis. The human FASL gene consists of approximately 8 kb and is split into 4 exons. Fas ligand/receptor interactions play an important role in the regulation of the immune system and the progression of cancer. Fas ligand or FasL is a homotrimeric type II transmembrane protein. It signals through trimerization of FasR, which spans the membrane of the "target" cell. This trimerization usually leads to apoptosis, or cell death. Soluble Fas ligand is generated by cleaving membrane-bound FasL at a conserved cleavage site by the external matrix metalloproteinase MMP-7.

application :

ELISA

homology :

No detectable cross-reactivity with any other cytokine.

sensitivity :

< 2 pg/ml

specificity :

There is no detectable cross-reactivity with other relevant proteins.

drywet surcharge :

Wet Ice

storage temperature :