ELISA/assay

Carbonic Anhydrase IX ELISA Kit (Human) : 96 Wells (OKAG00200)

OKAG00200

96 Wells

Application Kit

ELISA Kits

Carbonic Anhydrase IX ELISA Kit (Human) : 96 Wells (OKAG00200)

96 Wells

CA9

CAIX, CA-IX, Carbonate dehydratase IX, Carbonic anhydrase 9, Carbonic anhydrase IX, G250, Membrane antigen MN, MN, P54/58N, pMW1, RCC-associated antigen G250, Renal cell carcinoma-associated antigen G250

NM_001216.2

NP_001207.2

Q16790

Human

1 x 96-Well Plate or 12 x 8-Well Strips

Store as indicated in product manual.

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.

ELISA

Quantitative Colorimentric Sandwich ELISA

32 pg/mL

The Human Carbonic Anhydrase IX ELISA is capable of recognizing both recombinant and naturally produced Human Carbonic Anhydrase IX proteins. The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross-reactivity or interference.• Human: Carbonic Anhydrase XII, Carbonic Anhydrase XIV• Murine: Carbonic Anhydrase IX

Wet Ice

4C