ELISA/assay

E-Cadherin ELISA Kit (Human) : 96 Wells (OKAG00117)

OKAG00117

96 Wells

Application Kit

ELISA Kits

E-Cadherin ELISA Kit (Human) : 96 Wells (OKAG00117)

96 Wells

CDH1

Arc-1, Cadherin-1, CAM 120/80, CD324, CDHE, ECAD, E-cadherin, Epithelial cadherin, LCAM, UVO, uvomorulin, Uvomorulin

NM_001317184.1

NP_001304113.1

P12830

Human

1 x 96-Well Plate or 12 x 8-Well Strips

Store as indicated in product manual.

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.

ELISA

Quantitative Colorimentric Sandwich ELISA

188 pg/mL

The Human E-Cadherin ELISA is capable of recognizing both recombinant and naturally produced Human E-Cadherin proteins. The antigens listed below were tested at 60 ng/ml and exhibited less than 2% cross reactivity.• Murine: E-CadherinThe antigens listed below were tested at 120 ng/ml and did not exhibit significant cross reactivity or interference.• Human: N-Cadherin, P-Cadherin, VE-Cadherin• Murine: P-Cadherin

Wet Ice

4C