IL15 ELISA Kit (Human) : 48 Wells (OKAA00017-48W) | Aviva Systems Biology OKAA00017 product information

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product summary

company name :

Aviva Systems Biology

product type :

ELISA/assay

product name :

IL15 ELISA Kit (Human) : 48 Wells (OKAA00017-48W)

catalog :

OKAA00017

quantity :

48 Wells

product information

sku :

OKAA00017

product type :

Application Kit

category :

ELISA Kits

name :

IL15 ELISA Kit (Human) : 48 Wells (OKAA00017-48W)

size :

48 Wells

gene symbol :

IL15

alias symbols :

IL-15, Interleukin-15, MGC9721

nucleotide accession num :

NM_000585

protein accession num :

NP_000576

swissprot id :

P40933

species reactivity :

Human

description of target :

The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other s activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.

application :

ELISA

homology :

Human

assay info :

Assay Method: Quantitative Sandwich ELISA

sensitivity :

4 pg/ml

specificity :

This assay recognizes both natural and recombinant human IL-12p70. The factors listed below were prepared at 50ng/ml in Standard /sample Diluent and assayed for cross-reactivity and no significant cross-reactivity or interference was observed.Recombinant human: IL-12, IL-23p40, IL-12p35, IL-23 Recombinant mouse: IL-12 Recombinant rat:

drywet surcharge :

Wet Ice

storage temperature :