ELISA/assay

IL12B ELISA Kit (Human) : 48 Wells (OKAA00015-48W)

OKAA00015

48 Wells

Application Kit

ELISA Kits

IL12B ELISA Kit (Human) : 48 Wells (OKAA00015-48W)

48 Wells

IL12B

CLMF, CLMF2, CLMF p40, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12B, IL-12 subunit p40, Interleukin-12 subunit beta, NK cell stimulatory factor chain 2, NKSF, NKSF2

NM_002187

NP_002178

P29460

Human

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 4 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.

ELISA

Human

Assay Method: Quantitative Sandwich ELISA

30 pg/ml

This assay recognizes both natural and recombinant human IL-10. The factors listed below were prepared at 100ng/ml in Standard /sample Diluent and assayed for cross-reactivity and no significant cross-reactivity or interference was observed.Recombinant human: IL-1a, IL-1b, IL-2, IL-3, IL-4 Recombinant mouse: IL-1a, IL-1b, IL-2, IL-5 Recombinant rat : IL-1a, IL-1b, IL-2, IL-4, IL-6

Wet Ice

4C