ELISA/assay

IL10 ELISA Kit (Human) : 48 Wells (OKAA00014-48W)

OKAA00014

48 Wells

Application Kit

ELISA Kits

IL10 ELISA Kit (Human) : 48 Wells (OKAA00014-48W)

48 Wells

IL10

CSIF, Cytokine synthesis inhibitory factor, IL-10, IL10A, Interleukin-10, MGC126450, MGC126451, TGIF

NM_000572

NP_000563

P22301

Human

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

ELISA

Human

Assay Method: Quantitative Sandwich ELISA

7 pg/ml

This assay recognizes both natural and recombinant human IL-10. The factors listed below were prepared at 100ng/ml in Standard /sample Diluent and assayed for cross-reactivity and no significant cross-reactivity or interference was observed.Recombinant human: IL-1a, IL-1b, IL-2, IL-3, IL-4, Recombinant mouse: IL-1a, IL-1b, IL-2, IL-5, Recombinant rat : IL-1a, IL-1b, IL-2, IL-4, IL-6.

Wet Ice

4C