Anti-Periostin, C-terminal (OAPC00052) | Aviva Systems Biology OAPC00052 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

Anti-Periostin, C-terminal (OAPC00052)

catalog :

OAPC00052

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, chicken

application :

western blot, immunohistochemistry

product information

sku :

OAPC00052

product type :

Polyclonal Antibody

category :

Polyclonal

name :

Anti-Periostin, C-terminal (OAPC00052)

size :

100 ul

gene symbol :

POSTN

protein accession num :

NP_001185694.1

swissprot id :

Q62009

species reactivity :

Human, Mouse, Rat, Chicken

product format :

Liquid. PBS with no preservative. Adequate amount of material to conduct 10 mini Western Blots.

reconstitution and storage :

For long term storage -80 C is recommended, but shorter term storage at -20 C is also acceptable. Stable for a minimum of 1 year at -20 C. Avoid freeze/thaw cycles.

description of target :

Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading (Kruzynska-Frejtag A. et al., 24). Periostin has since been demonstrated to be important in heart valve development and myocardial infarction because it promotes collagen fibrogenesis, inhibits differentiation of progenitor cells into cardiomyocytes and is essential in maintaining the biomechanical properties of the adult myocardium (Norris et al., 28).

host :

Rabbit

application :

WB, IHC

homology :

Human; Mouse; Rat; Chicken

purification :

Prepared from rabbit serum by affinity purification using a column to which the fusion protein immunogen was coupled.

clonality :

Polyclonal

specificity :

Specific for the ~93 kDa periostin doublet in mouse lung extract. Consistent with the fact that this antibody is made against an alternatively spliced region of periostin, this antibody recognizes only the largest two of the three forms of periostin recognized on Western blots by the Pan periostin antibody (Cat. # OAPC00053) and also shows a distinctive staining pattern by immunohistochemistry (data not shown). The antibody works well for immunohistochemistry on paraformaldehyde-fixed sections with a simple antigen-retrieval protocol (incubate slides for 20 minutes at 90 C in 10 mM sodium citrate (pH 6.0)/ 0.1 % Tween-20).

immunogen :

Bacterial fusion protein equivalent to a 188-amino acid polypeptide from the C-terminal region of mouse periostin which is comprised of six small alternatively-spliced exons.

application info :

IHC 1:1000WB 1:1000

drywet surcharge :

Wet Ice

storage temperature :

-20C