PFKFB3 Antibody (Phospho-Ser467) (OABF01219) | Aviva Systems Biology OABF01219 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

PFKFB3 Antibody (Phospho-Ser467) (OABF01219)

catalog :

OABF01219

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section

product information

sku :

OABF01219

product type :

Polyclonal Antibody

category :

Polyclonal

name :

PFKFB3 Antibody (Phospho-Ser467) (OABF01219)

size :

100 ul

gene symbol :

PFKFB3

alias symbols :

PFK2, IPFK2,

swissprot id :

Q16875

species reactivity :

Human, Mouse, Rat

product format :

Liquid. Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

reconstitution and storage :

Store at -20 C for 12 months.

description of target :

6 Phosphofructo 2 Kinase plays a role in the synthesis and degradation of fructose 2,6-bisphosphate. Fructose-2,6-bisphosphate acts as an allosteric regulator of 6-phosphofructo-1-kinase (PFK1), which catalyses a key step in the glycoytic pathway. Glycolytic flux is key to tumour growth, and small molecule inhibition of 6 Phosphofructo 2 Kinase suppresses both glycolytic flux and tumour growth. Several lines of evidence suggest that 6 Phosphofructo 2 Kinase is also involved in obesity.

host :

Rabbit

application :

WB, IHC-P, Fluorescent-IHC

purification :

Purified by Protein A.

clonality :

Polyclonal

specificity :

This phosphorylated site is homologous to that of Ser467 in Mouse and Ser496 in Rat.

immunogen :

This PFKFB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 458-520 aa derived from human PFKFB3 around the phosphorylation site of Ser467

application info :

WB 1:300-1000IHC-P 1:200-400Fluorescent IHC 1:50-200

drywet surcharge :

Wet Ice

storage temperature :

-20C