BAX antibody - N-terminal region (AVARP02020_T100) | Aviva Systems Biology AVARP02020 product information

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product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

BAX antibody - N-terminal region (AVARP02020_T100)

catalog :

AVARP02020

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, dogs, bovine

application :

western blot, immunohistochemistry

product information

sku :

AVARP02020

product type :

Polyclonal Antibody

category :

Polyclonal

name :

BAX antibody - N-terminal region (AVARP02020_T100)

size :

100 ul

gene symbol :

BAX

alias symbols :

BCL2L4

nucleotide accession num :

NM_138761

protein accession num :

NP_620116

swissprot id :

Q07812

species reactivity :

Cow, Dog, Human, Pig

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMG
GEAPELALDPV
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

BAX encodes a protein that belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. BAX expression is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.

host :

Rabbit

application :

IHC, WB

homology :

Cow: 100%; Dog: 100%; Human: 100%; Pig: 100%

purification :

Protein A purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the N terminal region of human BAX

drywet surcharge :

Wet Ice

storage temperature :

-20C