TCHP antibody - C-terminal region (ARP60515_P050) | Aviva Systems Biology ARP60515 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

TCHP antibody - C-terminal region (ARP60515_P050)

catalog :

ARP60515

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, bovine

application :

western blot

product information

sku :

ARP60515

product type :

Polyclonal Antibody

category :

Polyclonal

name :

TCHP antibody - C-terminal region (ARP60515_P050)

size :

100 ul

gene symbol :

TCHP

alias symbols :

MGC10854, TpMs

nucleotide accession num :

NM_032300

protein accession num :

NP_115676

swissprot id :

Q9BT92

species reactivity :

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

IQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEE
SEKLKSARKQE
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.

host :

Rabbit

application :

homology :

Cow: 100%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Yeast: 91%

purification :

Affinity Purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the C terminal region of human TCHP

drywet surcharge :

Wet Ice

storage temperature :

-20C