IL1B antibody - N-terminal region (ARP54323_P050) | Aviva Systems Biology ARP54323 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

IL1B antibody - N-terminal region (ARP54323_P050)

catalog :

ARP54323

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dogs

application :

western blot, immunohistochemistry

product information

sku :

ARP54323

product type :

Polyclonal Antibody

category :

Polyclonal

name :

IL1B antibody - N-terminal region (ARP54323_P050)

size :

100 ul

gene symbol :

IL1B

alias symbols :

IL-1, IL1-BETA, IL1F2

nucleotide accession num :

NM_000576

protein accession num :

NP_000567

swissprot id :

P01584

species reactivity :

Dog, Horse, Human, Mouse, Rabbit

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDL
DLCPLDGGIQL
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. The gene encoding IL1B and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

host :

Rabbit

application :

IHC, WB

homology :

Dog: 92%; Horse: 86%; Human: 100%; Mouse: 75%; Rabbit: 92%

purification :

Affinity Purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the N terminal region of human IL1B

drywet surcharge :

Wet Ice

storage temperature :

-20C