TMPRSS6 antibody - N-terminal region (ARP53188_P050) | Aviva Systems Biology ARP53188 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

TMPRSS6 antibody - N-terminal region (ARP53188_P050)

catalog :

ARP53188

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, bovine

application :

western blot, immunohistochemistry

product information

sku :

ARP53188

product type :

Polyclonal Antibody

category :

Polyclonal

name :

TMPRSS6 antibody - N-terminal region (ARP53188_P050)

size :

100 ul

gene symbol :

TMPRSS6

alias symbols :

IRIDA

nucleotide accession num :

NM_153609

protein accession num :

NP_705837

swissprot id :

Q8IU80

species reactivity :

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

LLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESS
AFRSETAKAQK
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

TMPRSS6 is a serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. TMPRSS6 can also activate urokinase-type plasminogen activator with low efficiency. TMPRSS6 may play a specialized role in matrix remodeling processes in liver. TMPRSS6 is required to sense iron deficiency. Overexpression of TMPRSS6 suppresses activation of the HAMP promoter.The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.

host :

Rabbit

application :

IHC, WB

homology :

Cow: 100%; Dog: 93%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%

purification :

Affinity Purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS6

drywet surcharge :

Wet Ice

storage temperature :

-20C