GADD45B antibody - middle region (ARP48346_P050) | Aviva Systems Biology ARP48346 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

GADD45B antibody - middle region (ARP48346_P050)

catalog :

ARP48346

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, bovine

application :

western blot, immunohistochemistry

product information

sku :

ARP48346

product type :

Polyclonal Antibody

category :

Polyclonal

name :

GADD45B antibody - middle region (ARP48346_P050)

size :

100 ul

gene symbol :

GADD45B

alias symbols :

DKFZP566B133, GADD45BETA, MYD118

nucleotide accession num :

NM_015675

protein accession num :

NP_056490

swissprot id :

O75293

species reactivity :

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

FCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDLHC
LLVTNPHTDAW
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

The function of GADD45B is involved in the regulation of growth and apoptosis.This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

host :

Rabbit

application :

IHC, WB

homology :

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%

purification :

Affinity Purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the middle region of human GADD45B

drywet surcharge :

Wet Ice

storage temperature :

-20C