TMEM173 antibody - middle region (ARP48041_P050) | Aviva Systems Biology ARP48041 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

TMEM173 antibody - middle region (ARP48041_P050)

catalog :

ARP48041

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

sku :

ARP48041

product type :

Polyclonal Antibody

category :

Polyclonal

name :

TMEM173 antibody - middle region (ARP48041_P050)

size :

100 ul

gene symbol :

TMEM173

alias symbols :

FLJ38577, ERIS, MITA, MPYS, NET23, STING

nucleotide accession num :

NM_198282

protein accession num :

NP_938023

swissprot id :

Q86WV6

species reactivity :

Human, Pig

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

DPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLENGQRA
GTCVLEYATPL
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

TMEM173 acts as a facilitator of innate immune signaling. It is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. TMEM173 may be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.It also may be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.

host :

Rabbit

application :

homology :

Human: 100%; Pig: 83%

purification :

Affinity Purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the middle region of human TMEM173

drywet surcharge :

Wet Ice

storage temperature :

-20C