SPPL2B antibody - N-terminal region (ARP44989_P050) | Aviva Systems Biology ARP44989 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

SPPL2B antibody - N-terminal region (ARP44989_P050)

catalog :

ARP44989

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, bovine

application :

western blot, immunohistochemistry

product information

sku :

ARP44989

product type :

Polyclonal Antibody

category :

Polyclonal

name :

SPPL2B antibody - N-terminal region (ARP44989_P050)

size :

100 ul

gene symbol :

SPPL2B

alias symbols :

IMP4, KIAA1532, MGC111084, PSL1, IMP-4

nucleotide accession num :

NM_001077238

protein accession num :

NP_001070706

swissprot id :

Q8TCT7-4

species reactivity :

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

VARGNCTFYEKVRLAQGSGARGLLIVSRERLVPPGGNKT
QYDEIGIPVAL
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways.

host :

Rabbit

application :

IHC, WB

homology :

Cow: 86%; Dog: 86%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 86%; Rat: 86%

purification :

Affinity Purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the N terminal region of human SPPL2B

drywet surcharge :

Wet Ice

storage temperature :

-20C