GPNMB antibody - N-terminal region (ARP44499_P050) | Aviva Systems Biology ARP44499 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

GPNMB antibody - N-terminal region (ARP44499_P050)

catalog :

ARP44499

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, bovine

application :

western blot, immunohistochemistry

product information

sku :

ARP44499

product type :

Polyclonal Antibody

category :

Polyclonal

name :

GPNMB antibody - N-terminal region (ARP44499_P050)

size :

100 ul

gene symbol :

GPNMB

alias symbols :

HGFIN, NMB

nucleotide accession num :

NM_002510

protein accession num :

NP_002501

swissprot id :

Q14956

species reactivity :

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

DENDWNEKLYPVWKRGDMRWKNSWKGGRVQAVLTSDSPA
LVGSNITFAVN
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential.The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

host :

Rabbit

application :

IHC, WB

homology :

Cow: 100%; Dog: 79%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%

purification :

Affinity Purified

clonality :

Polyclonal

specificity :

100% homologous to both isoforms of hGPNMB

immunogen :

The immunogen is a synthetic peptide directed towards the N terminal region of human GPNMB

drywet surcharge :

Wet Ice

storage temperature :

-20C