BAG2 antibody - C-terminal region (ARP42177_T100) | Aviva Systems Biology ARP42177 product information

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product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

BAG2 antibody - C-terminal region (ARP42177_T100)

catalog :

ARP42177

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, bovine, zebrafish

application :

western blot, immunohistochemistry

product information

sku :

ARP42177

product type :

Polyclonal Antibody

category :

Polyclonal

name :

BAG2 antibody - C-terminal region (ARP42177_T100)

size :

100 ul

gene symbol :

BAG2

alias symbols :

RP3-496N17.2, BAG-2, KIAA0576, MGC149462, dJ417I1.2

nucleotide accession num :

NM_004282

protein accession num :

NP_004273

swissprot id :

O95816

species reactivity :

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

VDQKFQSIVIGCALEDQKKIKRRLETLLRNIENSDKAIK
LLEHSKGAGSK
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

BAG proteins compete with Hip for binding to the Hsc7/Hsp7 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc7 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc7 and inhibit its chaperone activity in a Hip-repressible manner.BAG proteins compete with Hip for binding to the Hsc7/Hsp7 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc7 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc7 and inhibit its chaperone activity in a Hip-repressible manner.

host :

Rabbit

application :

IHC, WB

homology :

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

purification :

Protein A purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the C terminal region of human BAG2

drywet surcharge :

Wet Ice

storage temperature :

-20C