MUC1 antibody - C-terminal region (ARP41445_P050) | Aviva Systems Biology ARP41445 product information

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product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

MUC1 antibody - C-terminal region (ARP41445_P050)

catalog :

ARP41445

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

product information

sku :

ARP41445

product type :

Polyclonal Antibody

category :

Polyclonal

name :

MUC1 antibody - C-terminal region (ARP41445_P050)

size :

100 ul

gene symbol :

MUC1

alias symbols :

CD227, EMA, PEM, PUM, mucin, KL-6, MAM6, PEMT, H23AG, MUC-1, MUC-1/X, MUC1/ZD, MUC-1/SEC

nucleotide accession num :

NM_001044390

protein accession num :

NP_001037855

swissprot id :

Q7Z552

species reactivity :

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Pig

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

GQLDIFPARDTYHPMSEYPTYHTHGRYVPPSSTDRSPYE
KVSAGNGGSSL
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 2 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 2 to 12 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.

host :

Rabbit

application :

IHC, WB

homology :

Cow: 92%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

purification :

Affinity Purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the C terminal region of human MUC1

drywet surcharge :

Wet Ice

storage temperature :

-20C