FGD1 antibody - N-terminal region (ARP38472_P050) | Aviva Systems Biology ARP38472 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

FGD1 antibody - N-terminal region (ARP38472_P050)

catalog :

ARP38472

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat, bovine

application :

western blot

product information

sku :

ARP38472

product type :

Polyclonal Antibody

category :

Polyclonal

name :

FGD1 antibody - N-terminal region (ARP38472_P050)

size :

100 ul

gene symbol :

FGD1

alias symbols :

AAS, FGDY, ZFYVE3, MRXS16

nucleotide accession num :

NM_004463

protein accession num :

NP_004454

swissprot id :

P98174

species reactivity :

Cow, Human, Pig, Rat

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

HGHRAPGGAGPSEPEHPATNPPGAAPPACADSDPGASEP
GLLARRGSGSA
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

host :

Rabbit

application :

homology :

Cow: 86%; Human: 100%; Pig: 86%; Rat: 79%

purification :

Affinity Purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the N terminal region of human FGD1

drywet surcharge :

Wet Ice

storage temperature :

-20C