ZNF265 antibody - N-terminal region (ARP37747_T100) | Aviva Systems Biology ARP37747 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

ZNF265 antibody - N-terminal region (ARP37747_T100)

catalog :

ARP37747

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, dogs, bovine, zebrafish

application :

western blot

product information

sku :

ARP37747

product type :

Polyclonal Antibody

category :

Polyclonal

name :

ZNF265 antibody - N-terminal region (ARP37747_T100)

size :

100 ul

gene symbol :

ZRANB2

alias symbols :

ZIS, ZIS1, ZIS2, ZNF265

nucleotide accession num :

NM_203350

protein accession num :

NP_976225

swissprot id :

Q5VV34

species reactivity :

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

RCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQC
KTCSNVNWARR
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

ZNF265 is a protein that has been shown to bind to the spliceosomal components U1-7K and U2AF35 and to direct alternative splicing. Analysis of the structure reveals substantial similarity to known RNA-binding motifs in terms of the distribution of key surface residues responsible for making RNA contacts, despite a complete lack of structural homology. An RNA gel shift assay was used to demonstrate that a single crossed finger domain from ZNF265 is capable of binding to an RNA message. Taken together, these results define a new RNA-binding motif and should provide insight into the functions of the >1 uncharacterized proteins in the sequence data bases that contain this domain.

host :

Rabbit

application :

homology :

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

purification :

Protein A purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF265

drywet surcharge :

Wet Ice

storage temperature :

-20C