DMTF1 Antibody - C-terminal region (ARP34602_P050) | Aviva Systems Biology ARP34602 product information

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product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

DMTF1 Antibody - C-terminal region (ARP34602_P050)

catalog :

ARP34602

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dogs

application :

western blot, immunohistochemistry

product information

sku :

ARP34602

product type :

Polyclonal Antibody

category :

Polyclonal

name :

DMTF1 Antibody - C-terminal region (ARP34602_P050)

size :

100 ul

gene symbol :

DMTF1

alias symbols :

DMP1, DMTF, MRUL, hDMP1

nucleotide accession num :

NM_001142326

protein accession num :

EAW76962

swissprot id :

Q9Y222

species reactivity :

Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

SFNDAHVSKFSDQNSTELMNSVMVRTEEEISDTDLKQEE
SPSDLASAYVT
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 4% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

host :

Rabbit

application :

IHC, WB

homology :

Dog: 92%; Guinea Pig: 91%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%

purification :

Affinity Purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the C terminal region of human DMTF1

drywet surcharge :

Wet Ice

storage temperature :

-20C