ATP7A antibody - N-terminal region (ARP33797_T100) | Aviva Systems Biology ARP33797 product information

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product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

ATP7A antibody - N-terminal region (ARP33797_T100)

catalog :

ARP33797

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, bovine

application :

western blot

product information

sku :

ARP33797

product type :

Polyclonal Antibody

category :

Polyclonal

name :

ATP7A antibody - N-terminal region (ARP33797_T100)

size :

100 ul

gene symbol :

ATP7A

alias symbols :

MK, MNK, DSMAX, SMAX3

nucleotide accession num :

NM_000052.5

protein accession num :

NP_000043

swissprot id :

Q04656

species reactivity :

Cow, Dog, Horse, Human, Mouse, Pig, Rat, Sheep

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

MKKQIEAMGFPAFVKKQPKYLKLGAIDVERLKNTPVKSS
EGSQQRSPSYQ
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

The ATP7A gene encodes the Menkes copper-translocating P-type ATPase, a ubiquitous protein that regulates the absorption of copper in the gastrointestinal tract. Inside cells, this protein has a dual function: it delivers copper to cuproenzymes in the Golgi compartment and effluxes excess copper. The trafficking mechanism and catalytic activity combine to facilitate absorption and intercellular transport of copper. Menkes disease, a systemic copper deficiency disorder, is caused by mutations in the ATP7A gene.

host :

Rabbit

application :

homology :

Cow: 93%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Sheep: 100%

purification :

Protein A purified

clonality :

Polyclonal

specificity :

The immunizing peptide used to raise this antibody is 100% homologous to isoform 3 (503aa 54.3kDa), 1 (1514aa, 165kDa), 2 (1581aa, 172kDa) and 5 (1422aa, 154kDa) of human ATP7A.

immunogen :

The immunogen is a synthetic peptide directed towards the N terminal region of human ATP7A

drywet surcharge :

Wet Ice

storage temperature :

-20C