CSEN antibody - N-terminal region (ARP31932_P050) | Aviva Systems Biology ARP31932 product information

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product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

CSEN antibody - N-terminal region (ARP31932_P050)

catalog :

ARP31932

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, zebrafish

application :

western blot, immunohistochemistry

product information

sku :

ARP31932

product type :

Polyclonal Antibody

category :

Polyclonal

name :

CSEN antibody - N-terminal region (ARP31932_P050)

size :

100 ul

gene symbol :

KCNIP3

alias symbols :

CSEN, DREAM, KCHIP3

nucleotide accession num :

NM_013434

protein accession num :

NP_038462

swissprot id :

Q9Y2W7

species reactivity :

Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

STVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGL
VDEDTFKLIYA
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.

host :

Rabbit

application :

IHC, WB

homology :

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

purification :

Affinity Purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the N terminal region of human CSEN

drywet surcharge :

Wet Ice

storage temperature :

-20C