GLI2 antibody - middle region (ARP31885_P050) | Aviva Systems Biology ARP31885 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

GLI2 antibody - middle region (ARP31885_P050)

catalog :

ARP31885

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

product information

sku :

ARP31885

product type :

Polyclonal Antibody

category :

Polyclonal

name :

GLI2 antibody - middle region (ARP31885_P050)

size :

100 ul

gene symbol :

GLI2

alias symbols :

HPE9, THP1, THP2

nucleotide accession num :

NM_030379

protein accession num :

NP_084655

swissprot id :

P10070

species reactivity :

Human

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and may contain up to 2% sucrose.

peptide sequence :

RNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVE
DCLHVRAIKTE
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

GLI2 encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.

host :

Rabbit

application :

IHC, WB

homology :

Human: 100%

purification :

Affinity Purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the N terminal region of human GLI2

drywet surcharge :

Wet Ice

storage temperature :

-20C