CALR antibody - C-terminal region (ARP30114_P050) | Aviva Systems Biology ARP30114 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Aviva Systems Biology

product type :

antibody

product name :

CALR antibody - C-terminal region (ARP30114_P050)

catalog :

ARP30114

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, zebrafish

application :

western blot, immunohistochemistry

product information

sku :

ARP30114

product type :

Polyclonal Antibody

category :

Polyclonal

name :

CALR antibody - C-terminal region (ARP30114_P050)

size :

100 ul

gene symbol :

CALR

alias symbols :

RO, CRT, SSA, cC1qR

nucleotide accession num :

NM_004343

protein accession num :

NP_004334

swissprot id :

P27797

species reactivity :

Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish

product format :

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

peptide sequence :

FGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEE
EAEDKEDDEDK
Synthetic peptide located within the following region:

reconstitution and storage :

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

description of target :

Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.

host :

Rabbit

application :

WB, IHC

homology :

Dog: 100%; Goat: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Yeast: 92%; Zebrafish: 79%

purification :

Affinity Purified

clonality :

Polyclonal

immunogen :

The immunogen is a synthetic peptide directed towards the C terminal region of human CALR

drywet surcharge :

Wet Ice

storage temperature :

-20C