This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-CD27 Molecule (CD27) antibody (FITC)
catalog :
ABIN951255
quantity :
0.1 mg
price :
286 USD
clonality :
monoclonal
host :
hamsters
conjugate :
FITC
clone name :
LG-3A10
reactivity :
mouse
application :
immunohistochemistry, flow cytometry, FACS, immunohistochemistry - frozen section
citations: 2
Reference
Henke A, Launhardt H, Klement K, Stelzner A, Zell R, Munder T. Apoptosis in coxsackievirus B3-caused diseases: interaction between the capsid protein VP2 and the proapoptotic protein siva. J Virol. 2000;74:4284-90 pubmed
Gravestein L, Nieland J, Kruisbeek A, Borst J. Novel mAbs reveal potent co-stimulatory activity of murine CD27. Int Immunol. 1995;7:551-7 pubmed
product information
Catalog Number :
ABIN951255
Product Name :
anti-CD27 Molecule (CD27) antibody (FITC)
Host Species :
Hamster
Clonality :
Monoclonal
Conjugation :
FITC
Antigen :
CD27
Product Type :
Primary
Size :
0.1 mg
List Price USD :
286 USD
List Of Pubmed ID :
7547681,10756043
Clone :
LG-3A10
Isotype :
IgG1
Product Description :
CD27 is part of the Tumor Necrosis Factor (TNF) family of receptors and is lymphocyte specific. Murine CD27 is expressed on the great majority of both αβ and γδ T lymphocytes, on a small population of peripheral B cells and on a very small subset of B220+ cells in the bone marrow. Murine CD27 is found on all thymocytes except a subset of CD4-CD8- precursors. There are two known basic functions of CD27 signaling. First, the binding of CD27 to CD70, a protein which is also expressed in T and B cells, provides costimulatory signals in lymphocyte proliferation and immunoglobulin production. Second, the association of CD27 with intracellular Siva, a proapoptotic protein, results in the induction of apoptotic events.Synonyms: CD27L receptor, T-cell activation antigen CD27, T14, TNFRSF7, Tumor necrosis factor receptor superfamily member 7
Immunogen :
MCD27 tag expressing clones AR0524 and AR0530 from Armenian Hamster spleen.
Reactivity :
Mouse (Murine)
Buffer :
PBS, 0.02 % Sodium Azide, EIA grade BSA to bring total protein concentration to 4-5 mg/mL
Concentration :
0.1 mg/mL
Application Summary :
Flow Cytometry (FACS),Functional Studies (Func),Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Uniprot ID :
P41272
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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