This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-Progesterone Receptor (PGR) (AA 922-933), (C-Term) antibody
catalog :
ABIN781660
quantity :
0.1 mg
price :
423.5 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PR-6A
reactivity :
human, chicken, domestic rabbit
application :
immunohistochemistry, immunohistochemistry - frozen section
citations: 5
Reference
Lee K, Dai Q, Hansen E, Saner C, Price T. Modulation of ATP-induced calcium signaling by progesterone in T47D-Y breast cancer cells. Mol Cell Endocrinol. 2010;319:109-15 pubmed publisher
Tetel M, Siegal N, Murphy S. Cells in behaviourally relevant brain regions coexpress nuclear receptor coactivators and ovarian steroid receptors. J Neuroendocrinol. 2007;19:262-71 pubmed
Price T, Hansen E, Oliver T. Immunofluorescent localization of a novel progesterone receptor(s) in a T47D-Y breast cancer cell line lacking genomic progesterone receptor expression. J Soc Gynecol Investig. 2005;12:610-6 pubmed
Bennett A, Greco B, Blasberg M, Blaustein J. Response to male odours in progestin receptor- and oestrogen receptor-containing cells in female rat brain. J Neuroendocrinol. 2002;14:442-9 pubmed
Frye C. The role of neurosteroids and non-genomic effects of progestins and androgens in mediating sexual receptivity of rodents. Brain Res Brain Res Rev. 2001;37:201-22 pubmed
product information
Catalog Number :
ABIN781660
Product Name :
anti-Progesterone Receptor (PGR) (AA 922-933), (C-Term) antibody
Host Species :
Mouse
Clonality :
Monoclonal
Antigen :
Progesterone Receptor
Product Type :
Primary
Size :
0.1 mg
List Price USD :
423.5 USD
List Of Pubmed ID :
20079401,11744087,17244199,16325750,12047719
Clone :
PR-6A
Isotype :
IgG2a
Product Description :
The progesterone receptor is an intracellular steroid receptor that specifically binds progesterone. Expressed by a single gene (chromosome 11q22), it has two main forms, A and B, that differ in their molecular weight. It has been proposed that expression of PR determination indicates a responsive estrogen receptor (ER) pathway, and therefore, may predict likely response to endocrine therapy in human breast cancer. A number of studies have shown that PR determination provides supplementary information to ER, in predicting response to endocrine therapy as well as estimating survival. PR has proved superior to ER as a prognostic indicator in some studies. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.Synonyms: NR3C3, Nuclear Receptor Subfamily 3 Group C Member 3, PGR, PR
Immunogen :
Peptide A922-K933. Epitope: C-terminal region.
Epitope :
AA 922-933,C-Term
Reactivity :
Chicken,Human,Rabbit
Buffer :
Stock solution contains PBS, pH 7.2 with 5 mg/mL BSA as stabilizer and 0.01 % Kathon as a preservative.
Concentration :
0.2 mg/mL
Application Summary :
Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Uniprot ID :
P06401
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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