This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 160-200), (pThr180), (pTyr182) antibody
catalog :
ABIN678668
quantity :
100 μL
price :
291.5 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry
product information
Catalog Number :
ABIN678668
Product Name :
anti-Mitogen-Activated Protein Kinase 14 (MAPK14) (AA 160-200), (pThr180), (pTyr182) antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Antigen :
P38 Mapk
Product Type :
Primary
Size :
100 μL
List Price USD :
291.5 USD
List Of Pubmed ID :
23508548
Image Legend :
Human MCF7 lysates probed with Rabbit Anti-p38 MAPK (Thr180+Tyr182) Polyclonal Antibody, Unconjugated at 1:5000 for 90 min at 37˚C.
Isotype :
IgG
Product Description :
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] Synonyms: RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA, Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Stress-activated protein kinase 2a, MAPK14 Subcellular locations: Cytoplasm, Nucleus
Immunogen :
KLH conjugated synthetic phosphopeptide derived from human p38 MAPK around the phosphorylation site of(Thr180/Tyr182)
Epitope :
pThr180,pTyr182,AA 160-200
Reactivity :
Human,Mouse (Murine),Rat (Rattus),Goat
Buffer :
Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Concentration :
1 μg/μL
Application Summary :
Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Uniprot ID :
Q16539
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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