This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 159-195), (Thr183), (Tyr185) antibody
catalog :
ABIN654887
quantity :
400 μL
price :
291.5 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
RB28968
reactivity :
human, mouse
application :
western blot, immunohistochemistry
product information
Catalog Number :
ABIN654887
Product Name :
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 159-195), (Thr183), (Tyr185) antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Antigen :
MAPK8
Product Type :
Primary
Size :
400 μL
List Price USD :
291.5 USD
List Of Pubmed ID :
20648623,20944115,20632440
Image Legend :
JNK1-T183/Y185 antibody (ABIN654887) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining
Clone :
RB28968
Isotype :
Ig
Product Description :
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. Synonyms: Mitogen-activated protein kinase 8,MAPK8,JNK1, PRKM8, SAPK1
Immunogen :
This MAPK8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-195 AA from human MAPK8.
Epitope :
AA 159-195,Thr183,Tyr185
Reactivity :
Human,Mouse (Murine)
Buffer :
PBS with 0.09 % (W/V) sodium azide
Concentration :
0.45 mg/mL
Application Summary :
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Western Blotting (WB)
Uniprot ID :
P45983
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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