This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (pThr450) antibody
catalog :
ABIN650890
quantity :
400 μL
price :
291.5 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
RB29255
reactivity :
human
application :
western blot
product information
Catalog Number :
ABIN650890
Product Name :
anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (pThr450) antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Antigen :
AKT1
Product Type :
Primary
Size :
400 μL
List Price USD :
291.5 USD
List Of Pubmed ID :
20808831
Image Legend :
Dot blot analysis of anti-Phospho-AKT1-T450 Antibody Phospho-specific Pab (ABIN650890) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6 µg/mL.
Clone :
RB29255
Isotype :
Ig
Product Description :
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]. Synonyms: RAC-alpha serine/threonine-protein kinase,AKT1,PKB, RAC
Immunogen :
This AKT1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T450 of human AKT1.
Epitope :
pThr450
Reactivity :
Human
Buffer :
PBS with 0.09 % (W/V) sodium azide
Concentration :
0.5 mg/mL
Application Summary :
Dot Blot (DB)
Uniprot ID :
P31749
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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