This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) (pSer536) antibody
catalog :
ABIN650886
quantity :
400 μL
price :
291.5 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
RB22552
reactivity :
human
application :
western blot
product information
Catalog Number :
ABIN650886
Product Name :
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) (pSer536) antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Antigen :
NF kappa B
Product Type :
Primary
Size :
400 μL
List Price USD :
291.5 USD
List Of Pubmed ID :
20729202,20639196
Image Legend :
Dot blot analysis of anti-Phospho-NF kappa B-S536 Phospho-specific Pab (ABIN650886) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6 µg/mL.
Clone :
RB22552
Isotype :
Ig
Product Description :
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine). Synonyms: Transcription factor p65,RELA,NFKB3
Immunogen :
This NF kappa B Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S536 of human NF kappa B.
Epitope :
pSer536
Reactivity :
Human
Buffer :
PBS with 0.09 % (W/V) sodium azide
Concentration :
0.31 mg/mL
Application Summary :
Dot Blot (DB)
Uniprot ID :
Q04206
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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