This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 1-335), (N-Term) antibody
catalog :
ABIN492380
quantity :
0.1 mL
price :
412.5 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AT8G4
reactivity :
human
application :
western blot, immunocytochemistry, enzyme immunoassay
citations: 2
Reference
Chuang D, Hough C, Senatorov V. Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases. Annu Rev Pharmacol Toxicol. 2005;45:269-90 pubmed
Mazzola J, Sirover M. Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders?. Neurotoxicology. 2002;23:603-9 pubmed
product information
Catalog Number :
ABIN492380
Product Name :
anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 1-335), (N-Term) antibody
Host Species :
Mouse
Clonality :
Monoclonal
Antigen :
GAPDH
Product Type :
Primary
Size :
0.1 mL
List Price USD :
412.5 USD
List Of Pubmed ID :
15822178,12428732
Clone :
AT8G4
Isotype :
IgG2b
Product Description :
Multiple roles for glyceraldehyde-3-phosphate dehydrogenase (GAPDH) have been recently appreciated. GAPDH is found in the particulate fractions, such as the nucleus, the mitochondria, and the small vesicular fractions. GAPDH gene expression is specifically increased during programmed neuronal cell death. When cells are exposed to various stressors, dynamic subcellular re-distribution of GAPDH occurs. GAPDH is also involved in various diseases, especially neurodegenerative disorders and cancers. As a membrane protein, GAPDH functions in endocytosis, in the cytoplasm, it is involved in the translational control of gene expression, in the nucleus, it functions in nuclear tRNA export, in DNA replication, and in DNA repair.Synonyms: CDABP0047, GAPD, Glyceraldehyde-3-Phosphate Dehydrogenase
Immunogen :
Recombinant human GAPDH (1-335aa) purified from E. coli
Epitope :
AA 1-335,N-Term
Reactivity :
Human
Buffer :
PBS, pH 7.4, 0.09 % Sodium azide
Concentration :
1.0 mg/mL
Application Summary :
Enzyme Immunoassay (EIA),Immunofluorescence (IF),Western Blotting (WB)
Uniprot ID :
P04406
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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