This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 305-323) antibody
catalog :
ABIN400973
quantity :
0.1 mL
price :
489.5 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dogs, chicken, bovine, chimpanzee, zebrafish
application :
western blot, immunohistochemistry, enzyme immunoassay
product information
Catalog Number :
ABIN400973
Product Name :
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 305-323) antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Antigen :
CAMK4
Product Type :
Primary
Size :
0.1 mL
List Price USD :
489.5 USD
List Of Pubmed ID :
8194751,1893997,2536634,8089075,8107230
Isotype :
IgG
Product Description :
CaM Kinase IV (also known as CAM kinase-GR, CAMK4 and CaMK IV) is a calcium/ calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. This kinase may be involved in the transcriptional regulation of microtubule dynamics. In vitro, CaMK IV phosphorylates CREB1, CREBBP, PRM2, MEF2A, MEF2D and STMN1/OP18. CaMK IV may also be involved in spermatogenesis and may play a role in the consolidation/ retention of hippocampusdependent long-term memory. CaMK IV must be phosphorylated to be maximally active and is phosphorylated by CAMKK1 or CAMKK2. In addition autophosphorylation of the N-terminus is equired for full activation. Autophosphorylation of Ser-336 allows the kinase to switch to a Ca(2+)/calmodulin-independent state. Most likely the kinase is inactivated by the serine/ threonine protein phosphatase 2A. CaMK IV is a monomer that is located within the cytoplasm and nucleus and substantial localization occurs in certain neuronal nuclei. In spermatids CaMK IV is associated with chromatin and the nuclear matrix. CaMK IV is also specifically expressed in epithelial ovarian cancer tissue.Synonyms: CAM kinase-GR, CaMK IV, Calcium/calmodulin-dependent protein kinase type IV
Immunogen :
Synthetic peptide corresponding to amino acids 305-323 of Human CaM Kinase IV protein
Epitope :
AA 305-323
Reactivity :
Chicken,Chimpanzee,Cow (Bovine),Dog (Canine),Frog,Human,Mouse (Murine),Rat (Rattus),Zebrafish (Danio rerio)
Buffer :
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative
Concentration :
70 mg/mL by Refractometry
Application Summary :
Enzyme Immunoassay (EIA),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Western Blotting (WB)
Uniprot ID :
Q16566
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
antibodies-online.com facilitates researchers to find the appropriate antibodies for their respective research project. As an independent and multi-vendor marketplace for research antibodies and thanks to the cooperation with more than 120 different manufacturers, we offer a large selection of Antibodies (over 500,000), ELISA Kits (over 200,000), Secondary Antibodies (13,000), Proteins (150,000), Peptides and Isotype Controls. In addition the scientists receive news and detailed information about the individual antibodies from databases such as the PubMed and others.
We help scientists to find the right products in our database. Similar products can be compared, our technical hotline offers consulting and the possibility to order directly with us.