This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) (Internal Region) antibody
catalog :
ABIN400823
quantity :
25 μL
price :
253 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6G8-B3-G5-C3
reactivity :
human, chimpanzee
application :
western blot, immunohistochemistry, enzyme immunoassay
citations: 4
Reference
Weng J, Luo J, Cheng X, Jin C, Zhou X, Qu J, et al. Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2. Proc Natl Acad Sci U S A. 2008;105:6081-6 pubmed publisher
Gao Y, Kitagawa K, Hiramatsu Y, Kikuchi H, Isobe T, Shimada M, et al. Up-regulation of GPR48 induced by down-regulation of p27Kip1 enhances carcinoma cell invasiveness and metastasis. Cancer Res. 2006;66:11623-31 pubmed
Loh E, Broussard S, Kolakowski L. Molecular characterization of a novel glycoprotein hormone G-protein-coupled receptor. Biochem Biophys Res Commun. 2001;282:757-64 pubmed
Hsu S, Liang S, Hsueh A. Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region. Mol Endocrinol. 1998;12:1830-45 pubmed
product information
Catalog Number :
ABIN400823
Product Name :
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) (Internal Region) antibody
Host Species :
Mouse
Clonality :
Monoclonal
Antigen :
LGR4 / GPR48
Product Type :
Primary
Size :
25 μL
List Price USD :
253 USD
List Of Pubmed ID :
18424556,17178856,11401528,9849958
Clone :
6G8-B3-G5-C3
Isotype :
IgG2b
Product Description :
LGR4, also known as leucine-rich repeat-containing G protein-coupled receptor 4, is a G protein-coupled receptors (GPCRs). GPCRs are membrane bound proteins that play key roles in a variety of physiologic functions. Members of the leucine-rich GPCR (LGR) family, such as GPR48, have multiple N-terminal leucinerich repeats (LRRs) and a 7-transmembrane domain. LGR4 is an orphan GPCR reported to be expressed in steroidogenic tissues such as placenta, ovary, testis, adrenal, pancreas, prostate, and thyroid, as well as in spinal cord, stomach, heart, and kidney.Synonyms: G-protein coupled receptor 48, Leucine-rich repeat-containing G-protein coupled receptor 4
Immunogen :
Synthetic peptide corresponding to an internal region of Human LGR4 protein
Epitope :
Internal Region
Reactivity :
Chimpanzee,Human,Macaque,Orang-Utan
Buffer :
0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide as preservative.
Concentration :
1.13 mg/mL (by UV absorbance at 280 nm)
Application Summary :
Enzyme Immunoassay (EIA),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Western Blotting (WB)
Uniprot ID :
Q9BXB1
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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