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product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 1252-1282), (C-Term) antibody
catalog :
ABIN357138
quantity :
0.4 mL
price :
357.5 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, FACS, enzyme immunoassay
product information
Catalog Number :
ABIN357138
Product Name :
anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 1252-1282), (C-Term) antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Antigen :
CD45 / LCA
Product Type :
Primary
Size :
0.4 mL
List Price USD :
357.5 USD
List Of Pubmed ID :
12716971,12595907,12556471,12626536,12519755
Isotype :
Ig
Product Description :
CD45 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. The CD45 gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling.Synonyms: L-CA, Leukocyte common antigen, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200
Immunogen :
KLH conjugated synthetic peptide between 1252~1282 amino acids from the C-terminal region of Human CD45. Genename: PTPRC
Epitope :
AA 1252-1282,C-Term
Reactivity :
Human
Buffer :
PBS with 0.09 % (W/V) Sodium Azide as preservative.
Concentration :
0.25 mg/mL
Application Summary :
Enzyme Immunoassay (EIA),Flow Cytometry (FACS),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Western Blotting (WB)
Uniprot ID :
P08575
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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