This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-CD44 (CD44) (AA 21-145) antibody
catalog :
ABIN263995
quantity :
0.1 mL
price :
412.5 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5c10
reactivity :
human
application :
western blot, immunohistochemistry, enzyme immunoassay
citations: 2
Reference
Cichy J, Pure E. The liberation of CD44. J Cell Biol. 2003;161:839-43 pubmed
Sneath R, Mangham D. The normal structure and function of CD44 and its role in neoplasia. Mol Pathol. 1998;51:191-200 pubmed
product information
Catalog Number :
ABIN263995
Product Name :
anti-CD44 (CD44) (AA 21-145) antibody
Host Species :
Mouse
Clonality :
Monoclonal
Antigen :
CD44
Product Type :
Primary
Size :
0.1 mL
List Price USD :
412.5 USD
List Of Pubmed ID :
9893744,12796473
Clone :
5C10
Isotype :
IgG2b
Product Description :
CD44 is a broadly distributed transmembrane glycoprotein that plays a critical role in a variety of cellular behaviors, including adhesion, migration, invasion, and survival. CD44 mediates cell-cell and cell-matrix interactions in a large part through its affinity for hyaluronan (HA), a glycosaminoglycan constituent of extracellular matrices, but also potentially through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Variants of CD44 are expressed in tissues during development, including embryonic epithelia. Known functions of CD44 are cellular adhesion (aggregation and migration), hyaluronate degradation, lymphocyte activation, lymph node homing, myelopoiesis and lymphopoiesis, angiogenesis, and release of cytokines. The functions of CD44 are principally dependant on cellular adhesion in one setting or another.Synonyms: CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein 1
Immunogen :
Recombinant Human CD44 (aa 21-145) purified from E. coli
Epitope :
AA 21-145
Reactivity :
Human
Buffer :
PBS, pH 7.4, containing 0.09 % Sodium Aziden as preservative.
Concentration :
1.0 mg/mL
Application Summary :
Enzyme Immunoassay (EIA),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Western Blotting (WB)
Uniprot ID :
P16070
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
antibodies-online.com facilitates researchers to find the appropriate antibodies for their respective research project. As an independent and multi-vendor marketplace for research antibodies and thanks to the cooperation with more than 120 different manufacturers, we offer a large selection of Antibodies (over 500,000), ELISA Kits (over 200,000), Secondary Antibodies (13,000), Proteins (150,000), Peptides and Isotype Controls. In addition the scientists receive news and detailed information about the individual antibodies from databases such as the PubMed and others.
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