This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-Non-POU Domain Containing, Octamer-Binding (NONO) (C-Term) antibody
catalog :
ABIN184024
quantity :
100 μg
price :
229 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat, dog, cow, common platanna
application :
western blot, immunohistochemistry, immunocytochemistry
citations: 2
Published Application/Species/DilutionReference
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, et al. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Genome Res. 2006;16:55-65 pubmed
Lazrek M, Goffard A, Schanen C, Karquel C, Bocket L, Lion G, et al. Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. Diagn Microbiol Infect Dis. 2006;55:55-8 pubmed
product information
Catalog Number :
ABIN184024
Product Name :
anti-Non-POU Domain Containing, Octamer-Binding (NONO) (C-Term) antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Antigen :
NONO
Product Type :
Primary
Size :
100 μg
List Price USD :
229 USD
List Of Pubmed ID :
16490339,16344560
Image Legend :
WB Suggested Anti-NONO Antibody Titration: 1.25 µg/mL ELISA Titer: 1:62500 Positive Control: HepG2 cell lysate
Product Description :
NONO is DNA- and RNA binding protein, involved in several nuclear processes. It binds the conventional octamer sequence in double stranded DNA. It also binds single-stranded DNA and RNA at a site independent of the duplex site. It is involved in pre-mRNA splicing and interacts with U5 snRNA. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs, be involved in DNA unwinding by modulating the function of topoisomerase I/TOP1 and be involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination and may stabilize paired DNA ends. NONO binds to an enhancer element in long terminal repeats of endogenous intracisternal A particles (IAPs) and activates transcription.
Immunogen :
Synthetic peptide directed towards the C terminal of human NONO
Epitope :
C-Term
Reactivity :
Cow (Bovine),Dog (Canine),Human,Mouse (Murine),Rat (Rattus),Xenopus laevis
Buffer :
PBS buffer with 2 % sucrose Note: This antibody may have up to 0.9% sodium azide in the buffer upon resuspension of the lyophilized pellet.
Concentration :
1 mg/mL
Application Summary :
Immunofluorescence (IF),Immunohistochemistry (IHC),Western Blotting (WB)
Uniprot ID :
Q15233
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
antibodies-online.com facilitates researchers to find the appropriate antibodies for their respective research project. As an independent and multi-vendor marketplace for research antibodies and thanks to the cooperation with more than 120 different manufacturers, we offer a large selection of Antibodies (over 500,000), ELISA Kits (over 200,000), Secondary Antibodies (13,000), Proteins (150,000), Peptides and Isotype Controls. In addition the scientists receive news and detailed information about the individual antibodies from databases such as the PubMed and others.
We help scientists to find the right products in our database. Similar products can be compared, our technical hotline offers consulting and the possibility to order directly with us.