This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Antibodies-online
product type :
antibody
product name :
anti-Interferon Regulatory Factor 5 (IRF5) (AA 176-240) antibody
catalog :
ABIN121152
quantity :
0.1 mL
price :
412.5 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10T1
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, enzyme immunoassay
citations: 3
Reference
Ning S, Huye L, Pagano J. Interferon regulatory factor 5 represses expression of the Epstein-Barr virus oncoprotein LMP1: braking of the IRF7/LMP1 regulatory circuit. J Virol. 2005;79:11671-6 pubmed
Barnes B, Kellum M, Pinder K, Frisancho J, Pitha P. Interferon regulatory factor 5, a novel mediator of cell cycle arrest and cell death. Cancer Res. 2003;63:6424-31 pubmed
Barnes B, Moore P, Pitha P. Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes. J Biol Chem. 2001;276:23382-90 pubmed
product information
Catalog Number :
ABIN121152
Product Name :
anti-Interferon Regulatory Factor 5 (IRF5) (AA 176-240) antibody
Host Species :
Mouse
Clonality :
Monoclonal
Antigen :
IRF5
Product Type :
Primary
Size :
0.1 mL
List Price USD :
412.5 USD
List Of Pubmed ID :
11303025,14559832,16140744
Image Legend :
Western blot analysis The extracts of Ramos, THP-1, A20 and NIH3T3 were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human IRF5 antibody (1:1,000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Clone :
10T1
Isotype :
IgG1
Product Description :
IRF-5 is a member of IRF family, which plays a critical role in the regulation of genes induced by viral infection, immunostimulation and cell growth regulation. The expression of IRF-5 is limited to lymphoid organs, dendritic cells, and peripheral blood lymphocytes, but is not expressed in numerous leukemia and lymphoma cell lines. Three IRFs(IRF-3, IRF-5, IRF-7) function as direct transducers of virus-mediated signaling and play a critical role in the expression of type I interferon genes and some chemokines.Synonyms: IRF-5, Interferon regulatory factor 5
Immunogen :
Recombinant human IRF-5 (176-240 aa) purified from E. coli
Epitope :
AA 176-240
Reactivity :
Human,Mouse (Murine)
Buffer :
PBS, pH 7.4, 0.09 % Sodium Azide
Concentration :
1.0 mg/mL
Application Summary :
Enzyme Immunoassay (EIA),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Immunoprecipitation (IP),Western Blotting (WB)
Uniprot ID :
Q13568
company information
Antibodies-online
Schloss-Rahe-Str. 15, 52072 Aachen
info@antibodies-online.com
http://www.antibodies-online.com
49 (0)241 95 163 153
headquarters: Germany
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